Four primes greater than $10$ that differ only in their last digit will need to have the corresponding number that ends in $5$ be divisible by $3$, so will be of the form $30m+k$, with $k$ values of $\{11,13,17,19\}$.
The last $3$ digits of their product $(30m+11)(30m+13)(30m+17)(30m+19)$ will be the same as the last $3$ digits of:
$\begin{align}& A+B+C \\
\text{where } &A:=900m^2(11\cdot13+11\cdot17+11\cdot19+13\cdot17+13\cdot 19+17\cdot19) \\
&B:= 30m(11\cdot13\cdot17+11\cdot13\cdot19+11\cdot17\cdot19+13\cdot17\cdot 19)\\
& C:=11\cdot 13\cdot17\cdot 19
\end{align}$
...because as soon as we have a factor of $1000$ in a term, it no longer affects the last three digits. Also because of this, we can simplify the first term above:
$\begin{align} A' &:= 900m^2(1\cdot3+1\cdot7+1\cdot9+3\cdot7+3\cdot 9+7\cdot9)\\
&= 900m^2(3+7+9+21+27+63) \\
&= 900m^2(120)
\end{align}$
Now we see that this first terms is divisible by $1000$ so is no longer interesting, so we can ignore it and proceed with $B$, the $30m$ term:
$\begin{align} B &= 30m(11\cdot13\cdot17+11\cdot13\cdot19+11\cdot17\cdot19+13\cdot17\cdot 19)\\
&= 30m(30\cdot13\cdot17+30\cdot11\cdot19) \\
&= 900m(221+209) \\
&= 900m(430) \\
\end{align}$
So $B$ is also divisible by $1000$ and the last $3$ digits will just match those of $C$, which doesn't depend on $m$.
$\begin{align} C &= 11\cdot13\cdot17\cdot 19)\\
&= 221 \cdot 209 \\
&= 46189 \\
\end{align}$
giving the last three digits as $189$ as claimed.