Let me answer the part of your question which I find reasonable:
Suppose that $\sigma$ is a complex structure on ${\mathbb R}^{2n}$ which is "standard at infinity". Then $\sigma$ is biholomorphic to the standard complex structure on ${\mathbb R}^{2n}$. The only interesting case is that of $n\ge 2$. I will prove more:
Theorem. Suppose that $M$ is a contractible complex manifold of dimension $n\ge 2$, $K\subset M$ is compact, $f: M - K \to {\mathbb C}^n$ is a biholomorphic map to the complement of a compact subset of ${\mathbb C}^n$. Then $f$ extends to a biholomorphic map $F: M\to {\mathbb C}^n$.
Proof.
Lemma. $f$ extends to a holomorphic map $F: M\to {\mathbb C}^n$.
Note that if $M$ were biholomorphic to ${\mathbb C}^n$, this would be just the Hartogs extension theorem. A version of the extension theorem though holds in our case due to the following fact: The compact subset $K\subset M$ is contained in a larger compact subset $C\subset M$ with Levi-convex smooth boundary. This larger subset is bounded by the preimage $f^{-1}(S)$ of a round sphere $S\subset {\mathbb C}^n$ of sufficiently large radius. Now you use, for instance the main theorem in (sadly, behind the Jstor paywall)
J. Kohn and H Rossi, On the extension of holomorphic functions from the boundary of a complex manifold. Ann. Math., 81 (1965), 451-472.
or Corollary 4.3 in (freely downloadable)
A. Andreotti, C. D. Hill, E. E. Levi convexity and the Hans Lewy problem. I and II, Ann. Scuola Norm. Sup. Pisa 26 (1972), 325–363, 747–806.
to extend $f|\partial C$ to a holomorphic function $C\to {\mathbb C}^n$. But, again, in view of Levi-convexity of $\partial C$, we also have local uniqueness of extension, which, therefore, coincides with $f$ on $M-K$. Hence, $f$ extends to the entire $M$: Use $F$ to define the extension on $C$ and $f$ to define the extension on $M-C$. qed
By the maximum principle, $F$ is surjective. Since $M$ is contractible, $M$ cannot contain any compact analytic subvarieties of positive dimension (since each such subvariety has a "fundamental class"). Therefore, point preimages for $F$ are finite. The map $F$ then is a local homeomorphism (use the fact that $det(dF)$ can vanish only only on a compact analytic subvariety whose image under $F$ would then have to be finite). Since $F$ is a proper map, it has to be a covering map. But its target is simply-connected, hence, $F$ is a homeomorphism. It is a standard fact (see e.g. [Griffiths-Harris, Principles of Algebraic Geometry p. 19]) that a holomorphic homeomorphism is in fact biholomorphic. Hence, $M$ is biholomorphic to ${\mathbb C}^n$. qed