I just want to elaborate a bit more on a point that the existing answers has made: The key to there being a "single" derivative on $\mathbb R$ and $\mathbb C$ is indeed because we have division in those sets (they are fields), but it's worth the time to think a little about what that changes.
Take a function $f$ on $\mathbb R$ (to $\mathbb R$, say). If we want to differentiate it at a point $x$, we look at the limit
$$
\lim_{h \to 0} \frac{f(x+h) - f(x)}{h}.
$$
One way of looking at this is to say that we start at $f(x)$ and deform the function a little in the direction $h$ to get $f(x+h)$, and look at how the deformations behave when we make the direction $h$ smaller and smaller.
Consider now a holomorphic function $f$ on $\mathbb C$ (again, let's say to $\mathbb C$). We can play the same game again to differentiate it at a point $z$: Deform it a little in a complex direction $h$, and look at how the deformations behave as the direction $h$ gets smaller and smaller.
Now let's take a function $f : \mathbb R^2 \to \mathbb R$. Again we fix a point $(x,y)$ and want to differentiate it at that point, so we try to play the deformation game again. But now we have a whole circle of directions we could deform the function in, and there is no single one that's better than the others, so we have to consider each one of them separately. This gives rise to the differential operator $D$ on $\mathbb R^2$ (or $\mathbb R^n$), where we both need to say at what point we want to differentiate our function, and in what direction, which corresponds to asking how the deformations of the function in that direction behave.
When we can divide things, there is only one direction to go into, so we get a privileged derivative kind of by accident.