Let's use $\oplus$ to mean "exclusive or" instead of the logical "$\lor$".
We define $$A \oplus B = (A\lor B) \land \lnot (A\land B) \equiv (A\land \lnot B) \lor (\lnot A \land B)$$
So we have the following premises:
$P\tag 1$
$P\rightarrow Q\tag 2$
$Q\oplus R\tag 3$
From premises (1) and (2), we can use modus ponens to conclude $$Q \tag 4$$
Now, from the definition of the exclusive-or above, $$Q \land (Q \oplus R) \tag{(3), (4)}$$
imply $\lnot R\tag{5}$
because $Q\oplus R = (Q\land \lnot R) \lor (\lnot Q \land R)\tag 3$
together with $Q = \lnot\lnot Q$ means that $(\lnot Q \land R)$ is false, giving us the use of the disjunctive syllogism to infer, therefore $Q \land \lnot R$, and using $\land$-elimination, we have $\lnot R$, as desired.