Consider an unbounded self-adjoint operator $A$ on a Hilbert space $\mathcal{H}$. Let $\mathcal{J} \subset \mathcal{H}$ a closed subspace reducing $A$, i.e. such that $P A \subset A P$ where $P$ denotes orthogonal projection onto $J$. Equivalently, $P \mathcal{D}(A) \subset \mathcal{D}(A)$ and $P A \psi = A P \psi$ for all $\psi \in \mathcal{D}(A)$. Then the restriction $A|\mathcal{J}$ is a densely defined operator on $\mathcal{J}$ with domain $\mathcal{D}(A) \cap \mathcal{J}$.
My question is this: is $A|\mathcal{J}$ again self-adjoint?
The reason I am interested in this question is the following: Take $\mathcal{H} = L^2(\mathbb{R}^{3N})$, and $\mathcal{J} = \Lambda L^2(\mathbb{R}^{3N})$, where the $\Lambda$ denotes the totally antisymmetric subspace, i.e. those functions $\psi(\vec{x_1},...,\vec{x_N})$ with the property that for any permutation $\sigma \in S^N$,
\begin{equation} \psi(\vec{x_{\sigma(1)}},...,\vec{x_{\sigma(N)}}) = sign(\sigma) \psi(\vec{x_1},...,\vec{x_N}) \end{equation}
Then $\mathcal{H}$ is the phase space of an atom consisting of $N$ electrons, with the nucleus fixed at the origin, and $\mathcal{J}$ is the phase space for the same system, but respecting the Pauli principle. My operator on $\mathcal{H}$ is the self-adjoint operator given by
\begin{equation} H^N = - \sum_{j=1}^{N} \Delta_j + \sum_{j = 1}^{N} V_{en}(x_j) + \sum_{i < j} V_{ee}(x_i - x_j) \end{equation}
where the $V_{ee}$ terms denote electron-electron repulsion, and $V_{en}$ electron-nucleus attraction.
In fact, in this case I know of a proof: since the Fourier transform maps antisymmetric functions to antisymmetric functions, one can first show that $H_0 = - \Delta$ is self-adjoint when restricted to $\mathcal{J}$. Then use the fact that the remaining terms are $H_0$-bounded with $H_0$-bound $0$, which remains true for the restriction.
I am aware of the related question at Selfadjoint operators. However, the case I am interested in is very different, in the sense that the restricted operator $A|\mathcal{J}$ is considered an operator on $\mathcal{J}$ rather than on the full Hilbert space $\mathcal{H}$. Indeed, considering $A|\mathcal{J}$ to be an operator on $\mathcal{H}$, it is in general (and certainly in my case) not even densely defined.