$$\left(\begin{matrix} a & b \\ c & d \end{matrix}\right)\left(\begin{matrix} d & -b \\ -c & a \end{matrix}\right)=\left(\begin{matrix} ad-bc & 0 \\ 0 & ad-bc \end{matrix}\right)$$
Thus if the determinant $ad-bc$ of the first matrix is an invertible (with respect to multiplication) element of the ring $R$, the inverse of the matrix is just the second matrix, divided by the determinant. However, if $ad-bc$ is not invertible, then we can use the fact that determinant of product is product of determinants to show that the determinant of any multiple of this matrix is not 1, thus we cannot obtain an identity matrix by multiplication.
So the matrix is invertible iff its determinant is invertible. For any field (e.g. real numbers) it is equivalent to the fact that the determinant is non-zero.