$\forall R\ \neg \forall X\ \exists x\ \forall y\ (R(x,y) \leftrightarrow X(y))$
Assuming that $R$ is a $2$-input predicate and $X$ is a $1$-input predicate, the given statement says that something holds for every such $R$. Well, what holds? Some $X$ exists such that... Specifically we can push the negations in, obtaining the equivalent:
$\forall R\ \exists X\ \forall x\ \exists y\ (\neg R(x,y) \leftrightarrow X(y))$
To help the intuition, let's restate $R$ as a 2d-array comprising rows, where $R(x,y)$ is the item in row $x$ and column $y$. Then "$\exists y\ (\neg R(x,y) \leftrightarrow X(y))$" compares a row of $R$ against $X$, so we can imagine $X$ to be a 1d-array arranged parallel to the rows of $R$. The statement then says:
Given any 2d-array $R$ of truth-values, there is a 1d-row $X$ of truth-values that, for every row in $R$, at some position gives the opposite truth-value.
Does that sound possible or impossible to you? It should also tell you how to prove or disprove it.