Here is a more principled solution. We have:
- $C \to A$ : so $C$ is "stronger" than $A$
- $A \land B \to C$: so there is something which joins with $A$ to form a statement stronger than $C$. The problem is that $A \land B$ might be strictly stronger than $C$.
In this case, what we need to do is to weaken $A \land B$ to something equivalent to $C$. Normally, we would weaken a statement with a $\lor$. In particular, we have $(A \land B) \lor C \leftrightarrow C$. However, $(A \land B) \lor C$ is not of the form $A \land D$.
We can use the distributive law to convert $(A \land B)\lor C$ to
$(A \lor C) \land (B \lor C)$. That is closer to what we want.
Now $A \lor C$ implies $A$, because $C$ implies $A$, and $A$ implies $A \lor C$, so we have $(A \lor C) \leftrightarrow A$.
Therefore, we have
$$
A \land (B \lor C) \leftrightarrow (A \lor C) \land (B \lor C) \leftrightarrow (A \land B) \lor C \leftrightarrow C.
$$
So we can take $D$ to be $B \lor C$. In general, $B \lor C$ is no stronger than $C$, but it could be strictly weaker.
Going back to the example in the question, "If a space is regular and second countable then it is metrizable. If a space is metrizable then it is regular.", we have
- A = "regular"
- B = "second countable"
- C = "metrizable"
- D = "metrizable or second countable", which is strictly weaker than $C$
so we have $C \leftrightarrow A \lor D$: "a space is metrizable if and only if it is regular and (metrizable or second countable)". Unfortunately, this is not very informative, which is expected. To get more informative equivalences, you'd have to look at what the words actually mean, rather than merely pushing around the logical connectives.
Finally, we can ask whether $B \lor C$ is the "weakest" solution the question. It is indeed, modulo $A$. In other words, if we have $A \land E \leftrightarrow C$ then $A \to (E \leftrightarrow B \lor C)$. For one direction, because $A \land E \to C$, we immediately have $A \to (E \to B \lor C)$. For the other direction, because $A \land (B \lor C)$ implies $C$, and $C$ implies $E$, so $A \to ( B \lor C \to E)$.