Let $\gamma $ denote a connected component of $\mathbb{C}- U$ which contains at least two points. If $\gamma $ is unbounded, $V=\mathbb{C}-\gamma$ is a simply connected region which is not the whole palne $\mathbb{C}$. Hence we can map $V$ onto $\mathbb{D}$ by a conformal map $f$, i.e. $f(V)=\mathbb{D}$. Since $U\subset V$, we see $f(U)\subset \mathbb{D}$. Therefore $U$ is analytically isomorphic to an open subset $f(U)$ of $\mathbb{D}$.
If $\gamma $ is a bounded set, $\mathbb{C}-\gamma$ is doubly connected in $\mathbb{C}$. The above argument does not work. So we consider the extended complex plane $\hat{\mathbb{C}}=\mathbb{C}\cup \{\infty\}$. Then $V=\hat{\mathbb{C}}-\gamma$ is simply connected in $\hat{\mathbb{C}}$.
Let $a,b\in\gamma $ and define $\varphi (z)=\frac{1}{z-a}$. Since $W=\varphi (V)$ is a simply connected open set which is not the whole palne $\mathbb{C}$, we can map $W$ onto $\mathbb{D}$ by a conformal map $g$. Note that $\varphi (U)\subset W$. Therefore $U$ is analytically isomorphic to an open subset $(g\circ\varphi )(U)$ of $\mathbb{D}$.