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Let $\{X_t\}_{t\geq0}$ be a stochastic process with state space $I=\{1,\ldots,n\}$ (that is, $I$ is the set of values that each $X_t$ may take) and call $c(t)=(P(X_t=1),\ldots,P(X_t=n))$.

Suppose the following model: $c'(t)=c(t)Q$, where $Q$ is an $n\times n$ matrix such that: $Q_{ii}\leq 0$, $Q_{ij}\geq0$ for $i\neq j$ and $\sum_{j=1}^n Q_{ij}=0$ for all $i$.

I would like to know if $\{X_t\}_{t\geq0}$ is a Markov chain in continuous time.

Intuition: I think this should be true: we have, for a very small $h$, $$\frac{P(X_{t+h}=j)-P(X_t=j)}{h}\approx \frac{d}{dt}P(X_t=j)=\sum_{i=1}^n P(X_t=i)\,Q_{ij}\;\;\Rightarrow$$ $$P(X_{t+h}=j)\approx\sum_{i\neq j}P(X_t=i)(h\,Q_{ij})+(1+h\,Q_{jj})P(X_t=j).$$ So, if we look the process at $h$ units of time, $X_{t+h}$ depends on the past only from $X_t$, that is, we have a discrete Markov chain.

Question: I would like a formal proof of $\{X_t\}_{t\geq0}$ being a Markov chain in continuous time.

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    There exists some Markov process $(Y_t)$ such that, for each $t$, the distributions of $X_t$ and $Y_t$ coincide -- but there is no reason why $(X_t)$ itself should be a Markov process. Consider for example $$c(t)=\begin{pmatrix}1/2\\1/2\end{pmatrix}\qquad Q=\begin{pmatrix}-1&1\\1&-1\end{pmatrix}$$ then $c(t)Q=0$ hence indeed $c'(t)=c(t)Q$ but we only know that every $X_t$ is uniform on $\{1,2\}$, which is definitely not enough to conclude that $(X_t)$ is a Markov process.2017-01-13
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    @Did Ok, I understand. And as a curiosity, why does there exist that process $(Y_t)$?2017-01-14
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    Because every generator $Q$ (in your context, this is a matrix with nonnegative off-diagonal entries, whose rows sum to zero) yields a Markov semi-group $(P_t)$ defined by $P_t=e^{tQ}$.2017-01-14

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