People don't necessarily want to do that, that's what they can prove resp work with. If $Lu = f$ with continuous $f$ and second order elliptic $L$, then in general $u$ is not in $C^2$. If, however, $f\in C^{0, \alpha}$, then it is often possible to show $u\in C^{2, \alpha}$. Similarly for parabolic equations. It just turns out that these spaces are particularly suited for PD operators, while the $C^k$ spaces are not.
And many will admit that this is not always convenient, since, for example, the Hölder spaces refuse to be separable.
Edit/added: (on a more technical note, it turns out that the Newton potential of a function $f$, defined by $N(f)(x):=C(n) \int \frac{f(y)}{|x-y|^{n-2}} dy$ (with a constant $C(n)$ depending on the dimension) is not a $C^2$ function if $f$ is merely continuous. The Newton potential is the basic building block for the Greens function of the Laplacian. (This is only correct if $n>2$, for $n=2$ a $\log|x-y|$ term replaces the $1/|x-y|^{n-2}$ term). $N(f)$ is, however, in $C^{2,\alpha}$ if $f\in C^{0,\alpha}$. Again, similar observations hold true in the parabolic case. A counterexample for the case $f\in C^0$ is given in exercise 4.9 in Gilbarg and Trudingers 'Elliptic Partial Differential Equations of Second Order').