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Is there a general method used to find the inverse Laplace transform. Are there any computational engines that will calculate the inverse directly?

For example, can a procedure be followed to find the inverse transform of $F(s) = \large\frac{2s+1}{s^2+9}$ or similar functions that involve "common" transforms?

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    Mathematica/Wolfram Alpha can calculate pretty much anything you can find in a table or can be manipulated fairly simply into forms that are (e.g. it will use partial fractions for you), but there are many it cannot do.2013-12-09

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I don't know of any direct computational method. But for quotients that consist of polynomial nominator and polynomial denominator, we usually write them as partial fractions:

$\frac{2s+1}{s^2+9} = 2\frac{s}{s^2+9} + \frac{1}{3}\frac{3}{s^2+9}$

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A related problem. The inverse Laplace transform is defined by,

$ f(x) = \frac{1}{2\pi i}\int_C F(s) {\rm e}^{st} ds \,$

where $F(s)$ is the Laplace transform of $f(x)$, and $C$ is the Bromwich contour (see below).

$ f(t) = \frac{1}{2\pi i} \int_C \frac{{(2s+1) e}^{st}}{(s^2+9)} ds =\frac{1}{2\pi i} \int_C \frac{{(2s+1) e}^{st}}{(s+3i)(s-3i)} ds$ $=\lim_{s\to -3i} (s+3i)\frac{{(2s+1) e}^{st}}{(s+3i)(s-3i)} + \lim_{s\to 3i} (s-3i)\frac{{(2s+1) e}^{st}}{(s+3i)(s-3i)}$

$= (1+\frac{i}{6})e^{-i3t} + (1-\frac{i}{6})e^{i3t} =2\cos(3x)+\frac{1}{3}\sin(3x). $

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It's a situation similar to finding antiderivatives. We need to know some standard inverse Laplace transforms or search them in a table. In this case since $\mathcal{L}^{-1}\left( \frac{s}{s^{2}+a^{2}}\right) =\cos at,$ $\mathcal{L}^{-1}\left( \frac{a}{ s^{2}+a^{2}}\right) =\sin at,$ and the Inverse Laplace Transform is linear, we have

$\begin{eqnarray*} \mathcal{L}^{-1}(F(s)) &=&\mathcal{L}^{-1}\left( \frac{2s+1}{s^{2}+9}\right) =\mathcal{L}^{-1}\left( \frac{2s}{s^{2}+9}\right) +\mathcal{L}^{-1}\left( \frac{1}{s^{2}+9}\right) \\ &=&2\mathcal{L}^{-1}\left( \frac{s}{s^{2}+9}\right) +\frac{1}{3}\mathcal{L} ^{-1}\left( \frac{3}{s^{2}+9}\right) \\ &=&2\cos 3t+\frac{1}{3}\sin 3t. \end{eqnarray*}$

Any rational function $P(s)/Q(s)$, where the degree of the polynomial $P(s)$ is lower than the degree of the polynomial $Q(s)$ can be expanded into partial fractions, each of them having a standard inverse Laplace Transform.

Another possibility is to use the Heaviside expansion formula $ \mathcal{L}^{-1}\left( \frac{P(s)}{Q(s)}\right) =\sum_{k=1}^{n}\frac{P(s_{k})}{Q^{\prime }(s_{k})}e^{s_{k}t}, $ where the $s_{k}$ are the distinct zeroes of $Q(s)$ (Schaum's Outline of Theory and Problems of Laplace Transforms by Murray Spiegel, Portuguese translation).