All right, I'll try to write this a bit more neatly than in robjohn's answer. He fully disposed of the exact answer; I'll address the approximation by the normal distribution.
It was Abraham de Moivre in the first half of the 18th century who introduced the bell-shaped curve into probability theory, showing that the density is $\varphi(x) = \text{constant}\cdot e^{-x^2/2}$ and finding the constant numerically. His friend James Stirling showed that the constant is $1/\sqrt{2\pi}.$ Today, the lower-case $\phi$ is standard notation for this function and capital $\Phi$ is its antiderivative that approaches $0$ at $-\infty$ and $1$ at $\infty$.
When one tosses a biased coin, one gets 1 head with probability $p$, or 0 heads with probability $1-p$. The expected value of that probability distribution is $0\cdot(1-p)+1\cdot p = p$. The standard deviation is $\sqrt{p(1-p)}$, and I leave the details to you unless you ask.
When one tosses it 100 times, and the tosses are independent, the expected value is $100p$ and the standard deviation is $\sqrt{100p(1-p)}$. For $p=0.4$, the expected value is 40 and the standard deviation is $\sqrt{100p(1-p)}\approx 4.898979485566$.
The probability that this is at least 50 is also the probability that it is strictly more than 49. The "continuity correction" calls for using the number half-way between those when doing the continuous approximation. That is $49.5$.
So the probability of getting 49 or fewer successes is $ \Phi\left(\frac{49.5 - 40}{4.898979485566}\right) \approx 0.97376. $ The probability of getting 50 or more successes is 1 minus that number.
The exact answer for $\le49$, if I can believe the software I'm using is about $0.9729008$.
If you use the continuity correction, then even with a sample of size 1 (where it would be silly---and worse, it would be pointless---to use the continuous approximation) the continuous approximation never differs from the exact result by more than about $0.03$. With six coin tosses, it gives somewhat respectable results. With 100, it is reasonably accurate.