You could write an equation for the plane, write another equation for the line and then solve the system of equations. Your plane vectors can be parameterized as follows:
$P=\{(0,0,0)+s(0,5,0)+t(0,0,5)\}$ $x=0, \qquad y=5s, \qquad z=5t$ Your line can be parameterized as well: $L=\{(10,1.5,1.5)+r[(10,1.5,1.5)-(5,1.5,1.5)]\}=\{(10,1.5,1.5)+r(5,0,0)\}$ $x=10+5r, \qquad y=1.5, \qquad z=1.5$ So for these to intersect, $x, y,$ and $z$ must be equal. You don't even necessarily need to solve these, just note that it is possible for them to all be equal in exactly one configuration...
Edit: This is basically just an explanation of what deinst was saying above in the comments.
You wanted to know how to solve these in general. Rather than do a literal "generalized" version, which would probably not shed much light on the subject, I will do another problem from the book I am working on (this is from Apostol Calculus Vol. I. section 13.8 # 10):
Let $L$ be the line through $(1,1,1)$ parallel to the vector $(2,-1,3)$, and let $M$ be the plane through $(1,1,-2)$ spanned by the vectors $(2,1,3)$ and $(0,1,1)$. Prove that there is one and only one point in the intersection $L\cap M$ and determine this point.
We start by defining $L=\{(1,1,1)+s(2,-1,3)\}$ $M=\{(1,1,-2)+t(2,1,3)+r(0,1,1)\}$
where $s,t,$ and $r$ are allowed to vary as scalars. From $L$ we have the following parameterizations: $x=1+2s, \qquad y=1-s, \qquad z=1+3s$ And from $M$ we have these parameterizations: $x=1+2t, \qquad y=1+t+r, \qquad z=-2+3t+r$
We are looking for the intersection of the line and the plane, and at this intersection (by definition) both requirements on the sets must hold. Thus the $x, y$, and $z$ values above must be the same (after all, a point is equal to another only if it's x, y, and z values are equal to each other). We are therefore motivated to remove the parameters, which are allowed to vary on their own in each parameterization. Use any method you would like to do this, so that you get the line and plane parameterizations "un-parameterized".
For the line: $y=1-s \implies s=1-y$. Substituting, $x=1+2(1-y)=3-2y$ and $z=1+3(1-y)=4-3y$
For the plane: solving for $s$ and $t$ in terms of $x$, $y$, and $z$ yields and substituting yields the Cartesian equation for the plane; or if you know how to create a normal vector you should be able to come up with the Cartesian equation pretty quickly: $-x-y+z=-4$
Now we simply substitute the equations we have for the line into the equation for the plane:
$-(3-2y)-y+(4-3y)=1-2y=-4 \implies y=\tfrac 5 2$
Now substituting back into the handy equations from the line, $x=3-2(\tfrac 5 2 )=-2, \qquad z=4-3(\tfrac 5 2)=\tfrac 7 2$
So $(-2, \tfrac 5 2, \tfrac {-7} 2)$ is the point of intersection between the line and the plane.
Now, since all of these results were necessarily true, any other point in the intersection would have to meet all of these requirements, all the way down to our result of the values for each cooridinate of the point. Therefore this is the only point in the intersection.
Sorry if this post was way to didactic, I was actually doing a lot of that for my own benefit, to make sure I could properly do this sort of problem.
The basic idea is to parameterize the information given, then "un-parameterize" it and solve the resulting set of simultaneous equations. This approach is entirely algebraic, and does not require determinants, though that would provide a truly more "general" solution.